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a portrait photo of dr Nicoletta Orphanou


Dr. Nicoletta Orphanou graduated from the First Faculty of Medicine, Charles University in Prague. With a great interest in cardiomyopathies she spent time as a research fellow at the dedicated centre of Molecular Cardiology and Inherited Cardiac Diseases - Fondazione Salvatore Maugeri, Pavia Italy.

She subsequently trained in cardiology at Nicosia General Hospital and General Hospital of Athens "G.Gennimatas" in Greece, while being an honorary attending fellow at Onassion Heart Surgery Centre at the Centre of Inherited Cardiac Diseases. 

As a consultant cardiologist, she further pursued a fellowship in echocardiography at the Royal Brompton Hospital, London, focusing on advanced transesophageal echocardiography of valve disorders and echocardiography in acute care medicine

Dr. Orphanou aims to ensure optimal care for her patients through fostering a strong doctor-patient relationship and effective communication.


Languages spoken: greek, english, italian

Cardiosurgeon Magdi Yacoub and dr Nicoletta Orphanou

With Sir Magdi Yacoub

dr Nicoletta Orphanou in front of a private plane

Special interests

  • Cardiomyopathies 

  • Inherited cardiac diseases

  • Valve disease

  • Echocardiography - Advanced transthoracic & transesophageal imaging


Orphanou N, Papatheodorou E, Anastasakis A. Dilated cardiomyopathy in the era of precision medicine: latest concepts and developments. Heart Fail Rev. 2022 Jul;27(4):1173-1191. doi: 10.1007/s10741-021-10139-0. Epub 2021 Jul 14. PMID: 34263412; PMCID: PMC8279384.

-  Orphanou N, Eftychiou C, Papasavvas E, Ioannides M, Avraamides P. Syncope in a hypertrophic heart at a wedding party: can happiness break a thick heart? Takotsubo cardiomyopathy complicated with left ventricular outflow tract obstruction in a hypertrophic heart. Oxf Med Case Reports. 2020 Jun 25;2020(6):omaa036. doi: 10.1093/omcr/omaa036. PMID: 32626581; PMCID: PMC7323591.

-  Mazzanti A, Ng K, Faragli A, Maragna R, Chiodaroli E, Orphanou N, Monteforte N, Memmi M, Gambelli P, Novelli V, Bloise R, Catalano O, Moro G, Tibollo V, Morini M, Bellazzi R, Napolitano C, Bagnardi V, Priori SG. Arrhythmogenic Right Ventricular Cardiomyopathy: Clinical Course and Predictors of Arrhythmic Risk. J Am Coll Cardiol. 2016 Dec 13;68(23):2540-2550. doi: 10.1016/j.jacc.2016.09.951. PMID: 27931611.

Awards & recognitions

- 2022 -

European Association of Cardiovascular Imaging (EACVI) -  Training grant winner

- 2021 -

European Examination in Core Cardiology


- 2013 -

Levention Scholarship winner

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